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Jun 22, 2022 | Gallbladder Management | 1 comment

 

What Causes Gallbladder Disease?

Have you ever been told you were diagnosed with Gallbladder disease because you are a female? Or maybe your mother and father had it? Western Medicine states that the risk factors for gallbladder disease is female, fat, fertile, fair and forty. But your Gallbladder diagnosis is much deeper than the 5 F’s and Genetics. Sure these can play a role with the development of gallbladder disease, but there are many other controllable factors that increase the risk. Many of them are preventable with lifestyle changes, while others are a result of existing health conditions.

Addressing the root cause of your gallbladder diagnosis is important to address if you are working to keep your gallbladder or reverse symptoms after gallbladder removal. There are many different causes, and its important you search for your root. Please see below: 

Chronic Inflammation

There is plenty of research on chronic inflammation and how it is linked to diseases like diabetes, heart disease, stroke, rheumatoid arthritis, allergies and COPD. However, chronic inflammation affects all tissues in the body, including the gallbladder. The WHO estimates that conditions resulting from chronic inflammation affect more than 60% of Americans and that number is expected to continue to increase over the coming years.1

Inflammation is a normal body process resulting from the body’s immune response sending out inflammatory cells and cytokines to heal itself and protect from pathogens. Inflammation becomes chronic when it lasts for a long period of time, anywhere from several months to years. Causes of chronic inflammation include toxins, bacteria, mold, parasites, auto immune conditions, chemicals in the environment, oxidative stress from free radical production, uric acid crystals (like those in gout), etc.1

Symptoms of chronic inflammation include:

  • Pain in the joints and muscles
  • Chronic fatigue
  • Mood disorders such as depression and anxiety
  • Irritable bowel
  • Acid reflux
  • Unintentional weight changes
  • Recurrent infections.

If you have symptoms like this, ask your doctor about having a blood test done to measure inflammatory markers.1

Cholecystitis

Inflammation of the gallbladder itself, or cholecystitis, is caused by gallstones blocking the bile duct or an illness that damages the gallbladder. Severe abdominal pain, fever, jaundice (yellowing of the skin and whites of the eyes), nausea and vomiting are symptoms. If you experience these symptoms, seek medical attention right away. Cholecystitis is a serious condition that can lead to sepsis (systemic infection) if left untreated. Treatment of cholecystitis includes pain management, IV fluids and often removal of the gallbladder.2

Poor gallbladder motility

Conditions like biliary dyskinesia and hyperkinetic gallbladder alter the effectiveness of the gallbladder. Biliary dyskinesia slows the movement of bile into the bile ducts, which can result in severe pain, especially after eating fatty meals. On the other hand, a hyperkinetic (or overactive) gallbladder results in digestive disturbance like intense pain and maldigestion of fat. Unfortunately, treatment for these conditions is typically gallbladder removal, especially if the symptoms are severe. 3,4

Poor Cholesterol Metabolism & Liver Congestion

Researchers are discovering that poor cholesterol metabolism is associated with a higher risk of gallbladder disease. Low HDL, high LDL, high total cholesterol and high triglycerides were associated with higher rates of gallstones. Most gallstones are made of cholesterol so poor cholesterol metabolism plays a role in the level of cholesterol in bile. Additionally, congestion of the liver can impact bile flow and composition increasing the risk of gallstones. When there are symptoms with gallstones, gallbladder removal is the recommended treatment. Lifestyle changes can greatly improve blood lipids and resulting risk for gallbladder disease.5,6

 Other causes:

  • Birth Control, HRT, testosterone therapy
  • Gluten intolerance/Celiac
  • Low thyroid function
  • PCOS
  • Parasites/dysbiosis/H. Pylori
  • Pregnancy
  • Menopause
  • Insulin resistance
  • Fast weight loss
  • Overeating
  • Fatty liver
  • Low stomach acid
  1. Nutrient deficiencies
  • Magnesium
  • Trace Minerals
  • Iron
  • Copper
  • Vitamin D

 If you are ready to get to the root cause of your gallbladder diagnosis and take back your health, check out the many support options here: https://www.gallbladderdiet.com/one-on-one-consultations/

 References

1.      Pahwa R, Goyal A, Jialal I. Chronic Inflammation. In: StatPearls [Internet]. StatPearls Publishing; 2022.

 

2.      McEACHERN CG. Acute Cholecystitis. Arch Surg. 1959;78(2):300. doi:10.1001/archsurg.1959.04320020122017

 

3.      Toouli J. Biliary dyskinesia. Curr Treat Options Gastroenterol. 2002;5(4):285-291. doi:10.1007/s11938-002-0051-9

 

4.      Williford ML, Fay KT, Simpson FJ, et al. Optimal management of the hyperkinetic gallbladder: A comparison of outcomes between operative and nonoperative approaches. Am Surg. 2021;87(6):903-909. doi:10.1177/0003134820966283

 

5.      Zhang M, Mao M, Zhang C, et al. Blood lipid metabolism and the risk of gallstone disease: a multi-center study and meta-analysis. Lipids Health Dis. 2022;21(1):26. doi:10.1186/s12944-022-01635-9

 

6.      Kalra A, Yetiskul E, Wehrle CJ, Tuma F. Physiology, Liver. In: StatPearls [Internet]. StatPearls Publishing; 2022.

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